Arsenal's Alex Iwobi gave Nigeria's thousands of fans inside Wembley hope two minutes after the break with a crisp finish but England - who had Raheem Sterling booked for diving - closed out the victory in relatively untroubled fashion.
Man Utd explained that the forward - who was criticised by Ten Hag on Friday for going out to celebrate his birthday in the wake of the defeat to City - was injured.
Jimenez fired home inside a crowded area after 70 minutes before Jota turned Luke Shaw insideout to add a second six minutes later and put the game beyond United.
The Brazilian struck the winner inside the last 10 minutes after good work from substitute Harvey Barnes, shortly after Fabian Schar had an effort ruled out for a foul in the build-up.
Chelsea were quick out of the blocks following the restart with Willian cutting inside before firing a strike just wide, however, things soon started to take a turn for the worse for the Blues.
Goals from Rakitic and Messi put Barca 2-0 up inside seven minutes but Mateo Kovacic reduced the deficit shortly after and Marco Asensio equalised nine minutes before half-time.
Luis Enrique's men comfortably notched another win to their unbeaten run as they breezed to victory against out-of-form Eibar with two goals either side of half-time Barcelona extended their unbeaten run in all competitions to 36 matches after
Antoine Griezmann had given France the lead through a penalty after just 12 minutes, Mbappe's impressive run being ended by Marcos Rojo inside the area.
The win moves Newcastle to within three points of fourth-placed Tottenham, while Chelsea's fifth league defeat of the season leaves them just inside the top half.
Davido and Omah Lay's voices pouring out of speakers, taking over the moment as Omah Lay gently sings, "Baby the weather is getting cold / Cold inside..." before Davido follows with the unforgettable line, "Sweet Fanta Diallo / I no fit forget
Aided by some dreadful defending from the home side, Lukaku slotted in from a couple of yards out - his 10th goal in nine games since joining from Everton in the summer.
Steven Berghuis reminded Brighton not to let their guard down as he struck the post for Ajax, but that was one of few chances for the visitors as the Seagulls closed out a comfortable win.