Lukaku is expected to miss the next two games after suffering concussion during United's draw with Southampton on Saturday. Ibrahimovic is not expected to return until February after being ruled out with a knee injury.
Although it was later revealed he had concussion, Karius inexplicably gave the ball to Karim Benzema to tap into an empty net. He followed that clanger up by dropping Gareth Bale's shot into the back of his own net.
Former Benfica keeper Ederson was examined further by City's medical staff but did not suffer concussion and returned to the bench, wearing a dressing, before the end of the game. The Brazilian later tweeted: "Hi, everyone - I am well.
Damian_Ancestor: "That guy he fell on, I heard the GUY is being admitted at ISOLO GENERAL right now ,from serious concussion." Watch video: Tiktok Video.
Mary Fowler suffered a mild concussion in training, while Kyah Simon is also nursing an injury problem. It leaves just Caitlin Foord as the only recognised striker available for Nigeria.
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Elsewhere, the use of five substitutes has now been introduced into the laws of the game but Ifab decided to extend trials of concussion substitutes for another 12 months 'to gather sufficient data to form a scientifically valid decision'.