Champions League winners, Liverpool will face Europa League holders Chelsea, in the annual clash between the victors of Europe's two main competitions.
The winner between Liverpool and Real will go onto a semi-final against either Chelsea or Porto, throwing up the possibility of an all-English last-four tie. Liverpool beat Chelsea in the semi-finals in 2005 and again in 2007.
Arsenal legend, Ian Wright, has predicted that Liverpool will get the better of Chelsea at Stamford Bridge this weekend, according to the UK Metro The Reds come into the game top of the Premier League with a perfect start to the campaign.
Chelsea manager, Frank Lampard, believes his personal touch saw him snatching Timo Werner from Liverpool's grasp. Werner was heavily linked with the Premier League champions, but eventually moved to Stamford Bridge in a £53 million deal.
Chelsea manager, Frank Lampard, has revealed that one of his priorities after replacing Maurizio Sarri, was to make Callum Hudson-Odoi aware of his first-team plans.
Ahead of Chelsea's match against Liverpool on Sunday, Lampard said: "It is hard because everyone has their own pathways. "Unfortunately for Mo, it didn't work out here but it is great credit to him.
"I still class Liverpool as favourites [on Sunday]. It's a tough game but if you had to pick Chelsea or Liverpool to come out on top in that game, you'd still fancy Liverpool."
Chelsea star, Eden Hazard has predicted the outcome of the Champions League between PSG and Liverpool. The Belgian also ruled out ever leaving Chelsea for PSG.
Liverpool manager, Jurgen Klopp, has dismissed Pep Guardiola's tongue-in-cheek congratulations, after he joked last week that the Reds had already won the Premier League title.
Providing his predictions, Merson told Sportskeeda: Brentford 0-2 Liverpool Burnley 1-3 Arsenal Newcastle United 2-1 Bournemouth Fulham 1-2 Aston Villa Nottingham Forest 2-1 West Ham United Tottenham 3-2 Wolves Manchester City 3-2 Chelsea Sheffield