Calhanoglu slotted home from the penalty spot when Lautaro Martinez was fouled by Theo Hernandez while substitute Frattesi tapped home a Mkhitaryan ball to add the fifth in injury time.
Dubravka produced a superb stop to deny Pablo Sarabia moments later, but Livramento bundled home his first Newcastle goal in stoppage time to put the seal on the Magpies' first home victory since their 3-0 win over Fulham on 16 December.
Shakthar equalized on the stroke of half-time, but Kane added three more in the second half, first nodding home a James Maddison cross, then slotting home a through-ball from Dejan Kulusevski and finally tapping in a parried save from goalkeeper
The visitors pressed home their advantage after the break as former Foxes midfielder N'Golo Kante, gifted time and space space, drilled home a drive from 30 yards.
Lively who is first hesitant (as he claims he's waiting for Cardi B to give her life to Christ so he can marry her), gives in to the pastor's persuation and follows Sister Amaka home. His experience at Sis. Amaka's home is best watched ???.
Zlatan Ibrahimovic scored twice on his home debut as Manchester United claimed a comfortable win over Southampton to maintain their 100% start to the Premier League season.