Klopp saw Liverpool suffer their second defeat of this season's Premier League campaign at St Mary's Stadium after Danny Ings's early goal for Southampton.
Match Day 3 kicks off on Sunday with a heavyweight clash at the Etihad Stadium between Manchester City and Arsenal, who are yet to score or win a single game.
Ronaldo is expected to lead his side in their next game which is against Luxembourg for the third World Cup Qualifier. The European champions won their first game 1-0 against Azerbaijan and are second in Group A behind Serbia.
Everton's Dominic Calvert-Lewin, Heung-Min Son of Tottenham Hotspur and Liverpool winger Mohammed Salah are joint-top of the scoring chart with 11 goals apiece after Game Week 13 fixtures.
Tottenham Hotspur forward, Heung-Min Son, leads the race for the Golden Boot this season, after Game Week 5 fixtures. Son scored one as Spurs were held to a pulsating 3-3 draw by West Ham on Sunday.
Backed by UEFA, the centre referee for the game, Danny Makkelie who publicly apologised for the mistake, has now dropped Diks from his set-up ahead of this summer's European Championship.
Moisés Caicedo put the home side ahead with his first Premier League goal after just 15 minutes and Marc Cucurella doubled the lead just four minutes after the re-start while Gross waltzed moments later put the game beyond the multiple league
Tottenham Hotspur forward, Heung-Min Son, is now in clear lead in the race for the Golden Boot this season, after Game Week 6 fixtures. Son scored the winner as Spurs saw off Burnley 1-0 on Monday night at Turf Moor.
Leicester City striker, Jamie Vardy and Everton's Dominic Calvert-Lewin lead the race for the Premier League's Golden Boot, following the completion of Game Week 3 fixtures on Monday.
Liverpool drew 3-3 at Watford in their opening game of the season, which Coutinho missed with a back injury. Ex-England defender Danny Mills told BBC Radio 5 live that Liverpool should "bite the bullet" and sell the 25-year-old.
Former England and Liverpool central midfielder, Danny Murphy has hailed the performances of Cesar Azpilicueta and Jorginho for Chelsea in their 2-0 victory over Pep Guardiola's Manchester City on Saturday.
He set up Alexandre Lacazette's late equaliser in the game. Despite playing all 90 minutes in midweek against Sporting in the Europa League, Emery is confident Iwobi can have a big effect in Sunday's match.
A former Liverpool midfielder, Danny Murphy, has urged Arsenal manager, Mikel Arteta to sign two players to take the Gunners to the next level after their FA Cup final victory over Chelsea on Saturday.