Midway through the second half Nunez glided past Toulouse keeper Guillaume Restes, but struck the post and was thankful to see Ryan Gravenberch score a fourth on the rebound.
But Chelsea got the break they needed in a tense finale when the VAR spotted Eberechi Eze had fouled Madueke just inside the area and the substitute expertly sent Palace keeper Dean Henderson the wrong way from the spot.
Cristiano Ronaldo had a penalty saved as Juventus drew for the sixth time in 12 Serie A games, this time against Atalanta. Federico Chiesa put the champions ahead with a fine strike from outside the box, his first league goal for Juve.
An entertaining encounter looked set to end in stalemate before - with the game entering stoppage time - Firmino soared to flash a header high past Spurs keeper Hugo Lloris from Andrew Robertson's corner.
Rather than risk losing the 28-year-old for nothing in a year's time, United could decide to cash for around £60million and put the funds towards this summer's big rebuild.
Luis Suarez sent the Spanish left-back flying down the left and Alba slid the ball across for Messi. The Argentine took his time before lobbing thekeeper and scoring for the sixth game in a row.
Jota got his second when he initially miscontrolled, but then recovered his poise to send a low shot beyond the Bournemouth keeper. Uruguay forward Nunez added the fourth in stoppage-time, diverting in Joe Gomez's cross.
But the midfielder's first goal in 22 games was cancelled out before half-time when a volley on the turn from Semi Ajayi, which appeared to be going wide, deflected off Ruben Dias and wrong-footed City keeper Ederson.
Faupala actually gave City hope when he scrambled in an equaliser, after Diego Costa headed Chelsea in front 10 minutes before half-time. The leveller was met with several coins being thrown onto the pitch from the Chelsea supporters' end.
Rakitic said Neuer was the difference between Sevilla and Bayern Munich in the UEFA Super Cup in Budapest, adding that thekeeper made two incredible saves to deny the La Liga side a victory against the Champions League holders.
The holders recovered from going behind to Rodrygo's early strike to lay siege to Real's goal, finally equalising 14 minutes from the end of normal time when Kevin de Bruyne pounced on Antonio Rudiger's clearance.
side of the pitch,move a little bit with the player and play athrough pass then you are 1 on1 with the goal keeper.Press square button together with R2 then it a goal.Tested and works on PES HOW TO DRIBBLE COVINENTLY Use a player withhalf brain