Arsenal have confirmed that the likes of Denis Suarez, Hector Bellerin, Rob Holding and Danny Welbeck will all miss their Europa League quarter-final second leg tie against Napoli on Thursday night.
According to a statement released through the club's official website, Suarez, Bellerin, Holding and Welbeck are all currently injured.
Arsenal defeated Napoli 2-0 in the first leg encounter last week Thursday at the Emirates Stadium.
"Denis Suarez has a groin injury which has seen the Arsenal midfielder remain in London, while defenders Hector Bellerin and Rob Holding are continuing their rehabilitation from long-term absences.
"The other man missing for the Gunners is forward Danny Welbeck. He is stepping up his training at the minute but is nowhere near ready for a return to the side, certainly not for a match of this magnitude," the statement read.
The kick-off time for the match is 8pm.
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