Liverpool will be without captain Jordan Henderson, who injured his right hamstring early in the 3-3 draw with Arsenal.
Defender Joel Matip could feature after a month out with a thigh injury.
Swansea full-back Kyle Naughton misses out after suffering a groin injury in Saturday's draw with Crystal Palace so Angel Rangel is set to deputise.
The Swans could also be without Leroy Fer, whose back problem will be assessed before the game.
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